loco Meaning, Definition & Usage

  1. adjective satellite informal or slang terms for mentally irregular
    wacky; loopy; bats; haywire; nuts; balmy; kooky; nutty; barmy; around the bend; buggy; kookie; loony; whacky; crackers; round the bend; daft; dotty; batty; cracked; fruity; bonkers.
    • it used to drive my husband balmy

WordNet


Lo"co adverb
Etymology
It.
Definitions
  1. (Mus.) A direction in written or printed music to return to the proper pitch after having played an octave higher.
Lo"co noun
Etymology
Sp. loco insane.
Definitions
  1. (Bot.) A plant (Astragalus Hornii) growing in the Southwestern United States, which is said to poison horses and cattle, first making them insane. The name is also given vaguely to several other species of the same genus. Called also loco weed.

Webster 1913